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2021-06-08

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Millions of J&J Covid-19 Vaccines Are at Risk of Expiring in June<blockquote>数百万J&J Covid-19疫苗面临6月过期风险</blockquote>

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Hospitals, state health departments and the federal government are racing to decide how to use up millions ofJohnson &amp; Johnson’sJNJ-0.68%Covid-19vaccine doses that are set to expire this month.<blockquote>各州、医院试图改变此类疫苗的路线，而出口疫苗的努力则面临障碍。医院、州卫生部门和联邦政府正在竞相决定如何用完将于本月到期的数百万剂强生公司JNJ-0.68%COVID-19疫苗。</blockquote> The prospect of so many doses going to waste in the U.S. whendeveloping nations are desperatefor shots would add pressure on the Biden administration to share stockpiled vaccines. But there are few practical solutions to administering them quickly in the U.S. or distributing them in time to foreign countries, according to those involved in the vaccination drive.<blockquote>当发展中国家迫切需要疫苗时，美国可能会浪费如此多的疫苗，这将增加拜登政府分享库存疫苗的压力。但据参与疫苗接种活动的人士称，几乎没有切实可行的解决方案可以在美国快速注射或及时分发给外国。</blockquote> The stockpile is, in part, an unintended consequence of the U.S.’s decision in April totemporarily suspend administrationof J&amp;J doses to assess a rare blood-clot risk. The pause forced states and providers tocancel large blocksof appointments that were never rescheduled, leaving a surplus of supply, andin some areas increasing hesitancyover the J&amp;J vaccine’s safety, according to industry officials.<blockquote>这种库存在一定程度上是美国四月份决定暂时停止使用强生剂量以评估罕见血栓风险的意外后果。据行业官员称，这一暂停迫使各州和供应商取消了大量从未重新安排的预约，导致供应过剩，一些地区对强生疫苗的安全性越来越犹豫。</blockquote> Some hospitals and states say that vaccines fromPfizerInc.and partnerBioNTech SE,as well asModernaInc.,are due to expire later this summer, but the stockpiles so far are largely of J&amp;J doses. Pfizer’s vaccine expires six months after manufacture. Moderna’s vaccine can remain frozen for up to six months, during which it can be refrigerated for one month.<blockquote>一些医院和州表示，辉瑞公司和partnerBioNTech SE以及asModernaInc.的疫苗将于今年夏天晚些时候到期，但迄今为止的库存主要是强生疫苗。辉瑞的疫苗在生产后六个月到期。Moderna的疫苗可以冷冻长达六个月，在此期间可以冷藏一个月。</blockquote> Philadelphia has 42,000 J&amp;J doses set to expire, most of which came from a Federal Emergency Management Agency clinic at the city’s convention center a few days before the pause, a city spokesman said. Pennsylvania, West Virginia, Oklahoma and Arkansas are among states that report having thousands of J&amp;J doses set to expire this month and have been unable to redistribute them.<blockquote>费城发言人表示，费城有42,000剂强生疫苗即将过期，其中大部分来自暂停前几天位于该市会议中心的联邦紧急事务管理局诊所。宾夕法尼亚州、西弗吉尼亚州、俄克拉荷马州和阿肯色州等州报告称，数千剂强生疫苗将于本月到期，但无法重新分配。</blockquote> “There’s no way at the end of June that we’re not going to have a couple thousand expiring,” said Danielle Hilborn, who helps oversee Covid-19 vaccines for McLaren Health Care Corp. The hospital system based outside Flint, Mich., has more than 3,500 J&amp;J doses set to expire this month, despite having moved doses among its hospitals and shipped 1,100 to a county health department.<blockquote>迈凯伦医疗保健公司(McLaren Health Care Corp.)帮助监督Covid-19疫苗的丹妮尔·希尔伯恩(Danielle Hilborn)表示：“到6月底，我们不可能不会有数千种疫苗过期。”密歇根州弗林特郊外的医院系统有超过3500剂J&amp;J疫苗将于本月到期，尽管它已经在医院之间转移了剂量，并将1100剂运送到了县卫生部门。</blockquote> Hospitals and public-health departments offering the shots have begun special promotions to use J&amp;J’s shots before they go bad. Some health systems have redistributed them inside and outside their networks, and some states have rerouted them to physician offices, pharmacies or other states.<blockquote>提供疫苗的医院和公共卫生部门已经开始特别促销，在强生的疫苗变质之前使用它们。一些卫生系统已经将它们在网络内外重新分配，一些州已经将它们重新路由到医生办公室、药房或其他州。</blockquote> The efforts have had limited success because of thenation’s slowdown in overall vaccinationsand because many states and vaccination sites also have expiring J&amp;J supply and don’t see demand for more doses. Just over half of the 21.4 million J&amp;J shots distributed to providers have been administered, according to data from the Centers for Disease Control and Prevention, versus 83% for shots from Moderna Inc. as well as Pfizer Inc. and its partner, BioNTech.<blockquote>这些努力取得了有限的成功，因为全国整体疫苗接种速度放缓，而且许多州和疫苗接种点的强生供应也即将到期，看不到对更多剂量的需求。根据美国疾病控制与预防中心的数据，分发给供应商的2140万剂强生疫苗中，只有一半多一点已经接种，而Moderna Inc.以及辉瑞公司及其合作伙伴BioNTech的疫苗接种比例为83%。</blockquote> J&amp;J stores doses frozen until shipment by the government, at which point they are refrigerated. Doses can be refrigerated for three months, and the drugmaker is studying whether the shelf life can be extended, a company spokesman said.<blockquote>J&amp;J将剂量冷冻储存，直到政府装运，然后冷藏。公司发言人表示，剂量可以冷藏三个月，制药商正在研究是否可以延长保质期。</blockquote> Many drugs and vaccines can remain effective for years, but all eventually start to lose potency. Typically, expiring prescription drugs and vaccines for other diseases are sent to other healthcare facilities, overseas or back to manufacturers, hospital officials said.<blockquote>许多药物和疫苗可以保持有效多年，但最终都会开始失去效力。医院官员表示，通常情况下，过期的处方药和其他疾病的疫苗会被送往海外的其他医疗机构或送回制造商。</blockquote> Covid-19 vaccines come with expiration information, which is determined by manufacturers based on testing data that is later cleared by regulators. Vaccines may still work after the expiration dates, according to manufacturing experts, but data was limited when the vaccines were authorized.<blockquote>新冠肺炎疫苗带有过期信息，这是由制造商根据测试数据确定的，然后由监管机构批准。据生产专家称，疫苗在有效期后可能仍然有效，但疫苗获得授权时的数据有限。</blockquote> The issue of expiring doses is the latest setback for J&amp;J’s Covid-19 vaccine effort. An accident at a contract manufacturer’s plant led to thecontamination of materialthat could have yielded up to 15 million doses and led to a halt in production of the J&amp;J vaccine there.<blockquote>过期剂量问题是强生新冠肺炎疫苗工作的最新挫折。一家合同制造商工厂发生事故，导致本可生产多达1500万剂疫苗的材料受到污染，并导致强生疫苗生产停止。</blockquote> Dr. Bechara Choucair, the White House vaccine coordinator, has briefed governors and local health officials on best practices to maximize supply, according to a White House official, who also cited ongoing U.S. Food and Drug Administration reviews of whether J&amp;J doses may have longer shelf lives. A second administration official said recalling doses that have already been shipped out to vaccination sites to potentially redistribute them would be logistically and legally challenging.<blockquote>据一名白宫官员称，白宫疫苗协调员Bechara Choucair博士已向州长和当地卫生官员简要介绍了最大限度增加供应的最佳做法。美国食品药品监督管理局审查强生剂量是否可能有更长的保质期。第二位政府官员表示，召回已经运往疫苗接种点的疫苗并可能重新分配，在后勤和法律上都具有挑战性。</blockquote> One of the administration officials said most Covid-19 vaccines in the U.S. aren’t close to expiring.<blockquote>一名政府官员表示，美国大多数新冠肺炎疫苗还没有接近过期。</blockquote> State health departments and hospital officials say the guidance from states and the CDC is to destroy or discard expired doses. The CDC didn’t respond to requests for comment.<blockquote>州卫生部门和医院官员表示，各州和疾病预防控制中心的指导是销毁或丢弃过期的剂量。疾病预防控制中心没有回应置评请求。</blockquote> In early April, U.S. regulators paused the use of J&amp;J’s vaccine after reports ofrare but severe blood clots. In response, vaccination sites across the country canceled thousands of appointments and instead offered people Pfizer or Moderna doses. Regulators lifted the pause 10 days later, with J&amp;J and regulators adding language to the vaccine’s label warning of a risk of blood clots.<blockquote>四月初，在有报道称出现罕见但严重的血栓后，美国监管机构暂停了强生疫苗的使用。作为回应，全国各地的疫苗接种点取消了数千次预约，转而向人们提供辉瑞或Moderna疫苗。10天后，监管机构解除了暂停，强生和监管机构在疫苗标签上添加了警告血栓风险的措辞。</blockquote> By then, patient demand for Covid-19 vaccines shifted from mass-vaccination to smaller community settings amid lingering concerns about the rare clots, according to industry and state officials.<blockquote>据行业和州政府官员称，到那时，由于对罕见血栓的担忧挥之不去，患者对Covid-19疫苗的需求从大规模疫苗接种转向了较小的社区环境。</blockquote> The regulatory pause and overall slowdown in vaccinations has left UofL Health in Louisville, Ky., with more than 6,000 J&amp;J doses that expire this month, after having administered about 2,600 since early April, said Dr. Jason Smith, chief medical officer. “My bet is that we will wind up wasting some of that, unfortunately,” he said.<blockquote>监管暂停和疫苗接种的整体放缓使得肯塔基州路易斯维尔的UofL Health。首席医疗官杰森·史密斯博士说，自4月初以来，已注射了约2600剂强生疫苗，本月将到期6000多剂强生疫苗。“不幸的是，我敢打赌，我们最终会浪费其中的一些，”他说。</blockquote> To use them, the health system is trying to reach physician offices outside its network, Dr. Smith said.<blockquote>史密斯博士说，为了使用它们，卫生系统正试图联系其网络之外的医生办公室。</blockquote> Pennsylvania’s Department of Health said it worked with the CDC and Chester County to try to transfer the county’s 50,000 expiring J&amp;J doses to Oregon. The deal fell through when Oregon experienced a decline in demand and no longer wanted them, a Pennsylvania health department spokesman said.<blockquote>宾夕法尼亚州卫生部表示，它与疾病预防控制中心和切斯特县合作，试图将该县5万剂即将过期的强生疫苗转移到俄勒冈州。宾夕法尼亚州卫生部门发言人表示，当俄勒冈州需求下降并且不再需要它们时，该交易失败了。</blockquote> The full extent of expiring Covid-19 vaccines is unknown because providers aren’t required to report it to the federal government, said Jessica Daley, a pharmacist and executive atPremierInc.,a large group-purchasing organization for hospitals.<blockquote>大型医院团购组织PremierInc.的药剂师兼高管杰西卡·戴利（Jessica Daley）表示，过期新冠肺炎疫苗的全部范围尚不清楚，因为供应商不需要向联邦政府报告。</blockquote> Premier is asking members whether they have expiring vaccines, and at least a dozen have said they have expiring J&amp;J doses, Ms. Daley said. “It’s not as simple as just moving the vaccine somewhere else,” she said.<blockquote>戴利女士说，Premier正在询问会员是否有过期的疫苗，至少有十几个人说他们有过期的强生疫苗。“这不仅仅是将疫苗转移到其他地方那么简单，”她说。</blockquote> Some states say they have asked the U.S. government whether doses can be shipped to developing nations. Doing so faces significant logistical and legal hurdles, according to the United Nations Children’s Fund, because those countries are wary of using vaccines after expiration dates and may not be able to administer them quickly.<blockquote>一些州表示，他们已经询问美国政府是否可以将疫苗运往发展中国家。联合国儿童基金会表示，这样做面临着重大的后勤和法律障碍，因为这些国家对使用过期疫苗持谨慎态度，可能无法快速接种。</blockquote>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Millions of J&J Covid-19 Vaccines Are at Risk of Expiring in June<blockquote>数百万J&amp;J Covid-19疫苗面临6月过期风险</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nMillions of J&J Covid-19 Vaccines Are at Risk of Expiring in June<blockquote>数百万J&amp;J Covid-19疫苗面临6月过期风险</blockquote>\n</h2>\n<h4 class=\"meta\">\n\nThe Wall Street Journal2021-06-08 21:04\n\n</h4>\n</header>\n<article>\n States, hospitals try to reroute such vaccines, while efforts to export them face hurdles. Hospitals, state health departments and the federal government are racing to decide how to use up millions ofJohnson &amp; Johnson’sJNJ-0.68%Covid-19vaccine doses that are set to expire this month.<blockquote>各州、医院试图改变此类疫苗的路线，而出口疫苗的努力则面临障碍。医院、州卫生部门和联邦政府正在竞相决定如何用完将于本月到期的数百万剂强生公司JNJ-0.68%COVID-19疫苗。</blockquote> The prospect of so many doses going to waste in the U.S. whendeveloping nations are desperatefor shots would add pressure on the Biden administration to share stockpiled vaccines. But there are few practical solutions to administering them quickly in the U.S. or distributing them in time to foreign countries, according to those involved in the vaccination drive.<blockquote>当发展中国家迫切需要疫苗时，美国可能会浪费如此多的疫苗，这将增加拜登政府分享库存疫苗的压力。但据参与疫苗接种活动的人士称，几乎没有切实可行的解决方案可以在美国快速注射或及时分发给外国。</blockquote> The stockpile is, in part, an unintended consequence of the U.S.’s decision in April totemporarily suspend administrationof J&amp;J doses to assess a rare blood-clot risk. The pause forced states and providers tocancel large blocksof appointments that were never rescheduled, leaving a surplus of supply, andin some areas increasing hesitancyover the J&amp;J vaccine’s safety, according to industry officials.<blockquote>这种库存在一定程度上是美国四月份决定暂时停止使用强生剂量以评估罕见血栓风险的意外后果。据行业官员称，这一暂停迫使各州和供应商取消了大量从未重新安排的预约，导致供应过剩，一些地区对强生疫苗的安全性越来越犹豫。</blockquote> Some hospitals and states say that vaccines fromPfizerInc.and partnerBioNTech SE,as well asModernaInc.,are due to expire later this summer, but the stockpiles so far are largely of J&amp;J doses. Pfizer’s vaccine expires six months after manufacture. Moderna’s vaccine can remain frozen for up to six months, during which it can be refrigerated for one month.<blockquote>一些医院和州表示，辉瑞公司和partnerBioNTech SE以及asModernaInc.的疫苗将于今年夏天晚些时候到期，但迄今为止的库存主要是强生疫苗。辉瑞的疫苗在生产后六个月到期。Moderna的疫苗可以冷冻长达六个月，在此期间可以冷藏一个月。</blockquote> Philadelphia has 42,000 J&amp;J doses set to expire, most of which came from a Federal Emergency Management Agency clinic at the city’s convention center a few days before the pause, a city spokesman said. Pennsylvania, West Virginia, Oklahoma and Arkansas are among states that report having thousands of J&amp;J doses set to expire this month and have been unable to redistribute them.<blockquote>费城发言人表示，费城有42,000剂强生疫苗即将过期，其中大部分来自暂停前几天位于该市会议中心的联邦紧急事务管理局诊所。宾夕法尼亚州、西弗吉尼亚州、俄克拉荷马州和阿肯色州等州报告称，数千剂强生疫苗将于本月到期，但无法重新分配。</blockquote> “There’s no way at the end of June that we’re not going to have a couple thousand expiring,” said Danielle Hilborn, who helps oversee Covid-19 vaccines for McLaren Health Care Corp. The hospital system based outside Flint, Mich., has more than 3,500 J&amp;J doses set to expire this month, despite having moved doses among its hospitals and shipped 1,100 to a county health department.<blockquote>迈凯伦医疗保健公司(McLaren Health Care Corp.)帮助监督Covid-19疫苗的丹妮尔·希尔伯恩(Danielle Hilborn)表示：“到6月底，我们不可能不会有数千种疫苗过期。”密歇根州弗林特郊外的医院系统有超过3500剂J&amp;J疫苗将于本月到期，尽管它已经在医院之间转移了剂量，并将1100剂运送到了县卫生部门。</blockquote> Hospitals and public-health departments offering the shots have begun special promotions to use J&amp;J’s shots before they go bad. Some health systems have redistributed them inside and outside their networks, and some states have rerouted them to physician offices, pharmacies or other states.<blockquote>提供疫苗的医院和公共卫生部门已经开始特别促销，在强生的疫苗变质之前使用它们。一些卫生系统已经将它们在网络内外重新分配，一些州已经将它们重新路由到医生办公室、药房或其他州。</blockquote> The efforts have had limited success because of thenation’s slowdown in overall vaccinationsand because many states and vaccination sites also have expiring J&amp;J supply and don’t see demand for more doses. Just over half of the 21.4 million J&amp;J shots distributed to providers have been administered, according to data from the Centers for Disease Control and Prevention, versus 83% for shots from Moderna Inc. as well as Pfizer Inc. and its partner, BioNTech.<blockquote>这些努力取得了有限的成功，因为全国整体疫苗接种速度放缓，而且许多州和疫苗接种点的强生供应也即将到期，看不到对更多剂量的需求。根据美国疾病控制与预防中心的数据，分发给供应商的2140万剂强生疫苗中，只有一半多一点已经接种，而Moderna Inc.以及辉瑞公司及其合作伙伴BioNTech的疫苗接种比例为83%。</blockquote> J&amp;J stores doses frozen until shipment by the government, at which point they are refrigerated. Doses can be refrigerated for three months, and the drugmaker is studying whether the shelf life can be extended, a company spokesman said.<blockquote>J&amp;J将剂量冷冻储存，直到政府装运，然后冷藏。公司发言人表示，剂量可以冷藏三个月，制药商正在研究是否可以延长保质期。</blockquote> Many drugs and vaccines can remain effective for years, but all eventually start to lose potency. Typically, expiring prescription drugs and vaccines for other diseases are sent to other healthcare facilities, overseas or back to manufacturers, hospital officials said.<blockquote>许多药物和疫苗可以保持有效多年，但最终都会开始失去效力。医院官员表示，通常情况下，过期的处方药和其他疾病的疫苗会被送往海外的其他医疗机构或送回制造商。</blockquote> Covid-19 vaccines come with expiration information, which is determined by manufacturers based on testing data that is later cleared by regulators. Vaccines may still work after the expiration dates, according to manufacturing experts, but data was limited when the vaccines were authorized.<blockquote>新冠肺炎疫苗带有过期信息，这是由制造商根据测试数据确定的，然后由监管机构批准。据生产专家称，疫苗在有效期后可能仍然有效，但疫苗获得授权时的数据有限。</blockquote> The issue of expiring doses is the latest setback for J&amp;J’s Covid-19 vaccine effort. An accident at a contract manufacturer’s plant led to thecontamination of materialthat could have yielded up to 15 million doses and led to a halt in production of the J&amp;J vaccine there.<blockquote>过期剂量问题是强生新冠肺炎疫苗工作的最新挫折。一家合同制造商工厂发生事故，导致本可生产多达1500万剂疫苗的材料受到污染，并导致强生疫苗生产停止。</blockquote> Dr. Bechara Choucair, the White House vaccine coordinator, has briefed governors and local health officials on best practices to maximize supply, according to a White House official, who also cited ongoing U.S. Food and Drug Administration reviews of whether J&amp;J doses may have longer shelf lives. A second administration official said recalling doses that have already been shipped out to vaccination sites to potentially redistribute them would be logistically and legally challenging.<blockquote>据一名白宫官员称，白宫疫苗协调员Bechara Choucair博士已向州长和当地卫生官员简要介绍了最大限度增加供应的最佳做法。美国食品药品监督管理局审查强生剂量是否可能有更长的保质期。第二位政府官员表示，召回已经运往疫苗接种点的疫苗并可能重新分配，在后勤和法律上都具有挑战性。</blockquote> One of the administration officials said most Covid-19 vaccines in the U.S. aren’t close to expiring.<blockquote>一名政府官员表示，美国大多数新冠肺炎疫苗还没有接近过期。</blockquote> State health departments and hospital officials say the guidance from states and the CDC is to destroy or discard expired doses. The CDC didn’t respond to requests for comment.<blockquote>州卫生部门和医院官员表示，各州和疾病预防控制中心的指导是销毁或丢弃过期的剂量。疾病预防控制中心没有回应置评请求。</blockquote> In early April, U.S. regulators paused the use of J&amp;J’s vaccine after reports ofrare but severe blood clots. In response, vaccination sites across the country canceled thousands of appointments and instead offered people Pfizer or Moderna doses. Regulators lifted the pause 10 days later, with J&amp;J and regulators adding language to the vaccine’s label warning of a risk of blood clots.<blockquote>四月初，在有报道称出现罕见但严重的血栓后，美国监管机构暂停了强生疫苗的使用。作为回应，全国各地的疫苗接种点取消了数千次预约，转而向人们提供辉瑞或Moderna疫苗。10天后，监管机构解除了暂停，强生和监管机构在疫苗标签上添加了警告血栓风险的措辞。</blockquote> By then, patient demand for Covid-19 vaccines shifted from mass-vaccination to smaller community settings amid lingering concerns about the rare clots, according to industry and state officials.<blockquote>据行业和州政府官员称，到那时，由于对罕见血栓的担忧挥之不去，患者对Covid-19疫苗的需求从大规模疫苗接种转向了较小的社区环境。</blockquote> The regulatory pause and overall slowdown in vaccinations has left UofL Health in Louisville, Ky., with more than 6,000 J&amp;J doses that expire this month, after having administered about 2,600 since early April, said Dr. Jason Smith, chief medical officer. “My bet is that we will wind up wasting some of that, unfortunately,” he said.<blockquote>监管暂停和疫苗接种的整体放缓使得肯塔基州路易斯维尔的UofL Health。首席医疗官杰森·史密斯博士说，自4月初以来，已注射了约2600剂强生疫苗，本月将到期6000多剂强生疫苗。“不幸的是，我敢打赌，我们最终会浪费其中的一些，”他说。</blockquote> To use them, the health system is trying to reach physician offices outside its network, Dr. Smith said.<blockquote>史密斯博士说，为了使用它们，卫生系统正试图联系其网络之外的医生办公室。</blockquote> Pennsylvania’s Department of Health said it worked with the CDC and Chester County to try to transfer the county’s 50,000 expiring J&amp;J doses to Oregon. The deal fell through when Oregon experienced a decline in demand and no longer wanted them, a Pennsylvania health department spokesman said.<blockquote>宾夕法尼亚州卫生部表示，它与疾病预防控制中心和切斯特县合作，试图将该县5万剂即将过期的强生疫苗转移到俄勒冈州。宾夕法尼亚州卫生部门发言人表示，当俄勒冈州需求下降并且不再需要它们时，该交易失败了。</blockquote> The full extent of expiring Covid-19 vaccines is unknown because providers aren’t required to report it to the federal government, said Jessica Daley, a pharmacist and executive atPremierInc.,a large group-purchasing organization for hospitals.<blockquote>大型医院团购组织PremierInc.的药剂师兼高管杰西卡·戴利（Jessica Daley）表示，过期新冠肺炎疫苗的全部范围尚不清楚，因为供应商不需要向联邦政府报告。</blockquote> Premier is asking members whether they have expiring vaccines, and at least a dozen have said they have expiring J&amp;J doses, Ms. Daley said. “It’s not as simple as just moving the vaccine somewhere else,” she said.<blockquote>戴利女士说，Premier正在询问会员是否有过期的疫苗，至少有十几个人说他们有过期的强生疫苗。“这不仅仅是将疫苗转移到其他地方那么简单，”她说。</blockquote> Some states say they have asked the U.S. government whether doses can be shipped to developing nations. Doing so faces significant logistical and legal hurdles, according to the United Nations Children’s Fund, because those countries are wary of using vaccines after expiration dates and may not be able to administer them quickly.<blockquote>一些州表示，他们已经询问美国政府是否可以将疫苗运往发展中国家。联合国儿童基金会表示，这样做面临着重大的后勤和法律障碍，因为这些国家对使用过期疫苗持谨慎态度，可能无法快速接种。</blockquote>\n<div class=\"bt-text\">\n\n\n 来源：<a href=\"https://www.wsj.com/articles/millions-of-j-j-covid-19-vaccines-are-at-risk-of-expiring-in-june-11623152775?mod=hp_lead_pos10\">The Wall Street Journal</a>\n为提升您的阅读体验，我们对本页面进行了排版优化\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"JNJ":"强生"},"source_url":"https://www.wsj.com/articles/millions-of-j-j-covid-19-vaccines-are-at-risk-of-expiring-in-june-11623152775?mod=hp_lead_pos10","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1135953958","content_text":"States, hospitals try to reroute such vaccines, while efforts to export them face hurdles.\n\nHospitals, state health departments and the federal government are racing to decide how to use up millions ofJohnson & Johnson’sJNJ-0.68%Covid-19vaccine doses that are set to expire this month.\nThe prospect of so many doses going to waste in the U.S. whendeveloping nations are desperatefor shots would add pressure on the Biden administration to share stockpiled vaccines. But there are few practical solutions to administering them quickly in the U.S. or distributing them in time to foreign countries, according to those involved in the vaccination drive.\nThe stockpile is, in part, an unintended consequence of the U.S.’s decision in April totemporarily suspend administrationof J&J doses to assess a rare blood-clot risk. The pause forced states and providers tocancel large blocksof appointments that were never rescheduled, leaving a surplus of supply, andin some areas increasing hesitancyover the J&J vaccine’s safety, according to industry officials.\nSome hospitals and states say that vaccines fromPfizerInc.and partnerBioNTech SE,as well asModernaInc.,are due to expire later this summer, but the stockpiles so far are largely of J&J doses. Pfizer’s vaccine expires six months after manufacture. Moderna’s vaccine can remain frozen for up to six months, during which it can be refrigerated for one month.\nPhiladelphia has 42,000 J&J doses set to expire, most of which came from a Federal Emergency Management Agency clinic at the city’s convention center a few days before the pause, a city spokesman said. Pennsylvania, West Virginia, Oklahoma and Arkansas are among states that report having thousands of J&J doses set to expire this month and have been unable to redistribute them.\n“There’s no way at the end of June that we’re not going to have a couple thousand expiring,” said Danielle Hilborn, who helps oversee Covid-19 vaccines for McLaren Health Care Corp. The hospital system based outside Flint, Mich., has more than 3,500 J&J doses set to expire this month, despite having moved doses among its hospitals and shipped 1,100 to a county health department.\nHospitals and public-health departments offering the shots have begun special promotions to use J&J’s shots before they go bad. Some health systems have redistributed them inside and outside their networks, and some states have rerouted them to physician offices, pharmacies or other states.\nThe efforts have had limited success because of thenation’s slowdown in overall vaccinationsand because many states and vaccination sites also have expiring J&J supply and don’t see demand for more doses. Just over half of the 21.4 million J&J shots distributed to providers have been administered, according to data from the Centers for Disease Control and Prevention, versus 83% for shots from Moderna Inc. as well as Pfizer Inc. and its partner, BioNTech.\nJ&J stores doses frozen until shipment by the government, at which point they are refrigerated. Doses can be refrigerated for three months, and the drugmaker is studying whether the shelf life can be extended, a company spokesman said.\nMany drugs and vaccines can remain effective for years, but all eventually start to lose potency. Typically, expiring prescription drugs and vaccines for other diseases are sent to other healthcare facilities, overseas or back to manufacturers, hospital officials said.\nCovid-19 vaccines come with expiration information, which is determined by manufacturers based on testing data that is later cleared by regulators. Vaccines may still work after the expiration dates, according to manufacturing experts, but data was limited when the vaccines were authorized.\nThe issue of expiring doses is the latest setback for J&J’s Covid-19 vaccine effort. An accident at a contract manufacturer’s plant led to thecontamination of materialthat could have yielded up to 15 million doses and led to a halt in production of the J&J vaccine there.\nDr. Bechara Choucair, the White House vaccine coordinator, has briefed governors and local health officials on best practices to maximize supply, according to a White House official, who also cited ongoing U.S. Food and Drug Administration reviews of whether J&J doses may have longer shelf lives. A second administration official said recalling doses that have already been shipped out to vaccination sites to potentially redistribute them would be logistically and legally challenging.\nOne of the administration officials said most Covid-19 vaccines in the U.S. aren’t close to expiring.\nState health departments and hospital officials say the guidance from states and the CDC is to destroy or discard expired doses. The CDC didn’t respond to requests for comment.\nIn early April, U.S. regulators paused the use of J&J’s vaccine after reports ofrare but severe blood clots. In response, vaccination sites across the country canceled thousands of appointments and instead offered people Pfizer or Moderna doses. Regulators lifted the pause 10 days later, with J&J and regulators adding language to the vaccine’s label warning of a risk of blood clots.\nBy then, patient demand for Covid-19 vaccines shifted from mass-vaccination to smaller community settings amid lingering concerns about the rare clots, according to industry and state officials.\nThe regulatory pause and overall slowdown in vaccinations has left UofL Health in Louisville, Ky., with more than 6,000 J&J doses that expire this month, after having administered about 2,600 since early April, said Dr. Jason Smith, chief medical officer. “My bet is that we will wind up wasting some of that, unfortunately,” he said.\nTo use them, the health system is trying to reach physician offices outside its network, Dr. Smith said.\nPennsylvania’s Department of Health said it worked with the CDC and Chester County to try to transfer the county’s 50,000 expiring J&J doses to Oregon. The deal fell through when Oregon experienced a decline in demand and no longer wanted them, a Pennsylvania health department spokesman said.\nThe full extent of expiring Covid-19 vaccines is unknown because providers aren’t required to report it to the federal government, said Jessica Daley, a pharmacist and executive atPremierInc.,a large group-purchasing organization for hospitals.\nPremier is asking members whether they have expiring vaccines, and at least a dozen have said they have expiring J&J doses, Ms. Daley said. “It’s not as simple as just moving the vaccine somewhere else,” she said.\nSome states say they have asked the U.S. government whether doses can be shipped to developing nations. Doing so faces significant logistical and legal hurdles, according to the United Nations Children’s Fund, because those countries are wary of using vaccines after expiration dates and may not be able to administer them quickly.","news_type":1,"symbols_score_info":{"JNJ":0.9}},"isVote":1,"tweetType":1,"viewCount":806,"commentLimit":10,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"symbols":[],"verified":2,"subType":0,"readableState":1,"langContent":"EN","currentLanguage":"EN","warmUpFlag":false,"orderFlag":false,"shareable":true,"causeOfNotShareable":"","featuresForAnalytics":[],"commentAndTweetFlag":false,"andRepostAutoSelectedFlag":false,"upFlag":false,"length":4,"xxTargetLangEnum":"ORIG"},"commentList":[],"isCommentEnd":true,"isTiger":false,"isWeiXinMini":false,"url":"/m/post/117476001"}