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{"i18n":{"language":"zh_CN"},"detailType":1,"isChannel":false,"data":{"magic":2,"id":860108150,"tweetId":"860108150","gmtCreate":1632143072070,"gmtModify":1632802576184,"author":{"id":4087128820555850,"idStr":"4087128820555850","authorId":4087128820555850,"authorIdStr":"4087128820555850","name":"MayW8","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"userType":1,"introduction":"","boolIsFan":false,"boolIsHead":false,"crmLevel":11,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":6,"starInvestorFlag":false},"themes":[],"images":[],"coverImages":[],"extraTitle":"","html":"<html><head></head><body><p>Like</p></body></html>","htmlText":"<html><head></head><body><p>Like</p></body></html>","text":"Like","highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"favoriteSize":0,"link":"https://laohu8.com/post/860108150","repostId":1194444021,"repostType":4,"repost":{"id":"1194444021","kind":"news","weMediaInfo":{"introduction":"Stock Market Quotes, Business News, Financial News, Trading Ideas, and Stock Research by Professionals","home_visible":0,"media_name":"Benzinga","id":"1052270027","head_image":"https://static.tigerbbs.com/d08bf7808052c0ca9deb4e944cae32aa"},"pubTimestamp":1632141554,"share":"https://www.laohu8.com/m/news/1194444021?lang=zh_CN&edition=full","pubTime":"2021-09-20 20:39","market":"us","language":"en","title":"Cannabis Edibles are Leading to More Negative Outcomes in Cannabis Users<blockquote>大麻食品正在给大麻使用者带来更多负面后果</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1194444021","media":"Benzinga","summary":"The legalization of recreational marijuana use has broadly increased the availability of cannabis an","content":"<p>The legalization of recreational marijuana use has broadly increased the availability of cannabis and the number of cannabis users. In the latest information (2019) compiled bySAMHSA, an estimated 31.5m individuals over 12 in the US used cannabis in the last month. These rates are growing at approximately 10% per year, with the largest growth in use by adults over 26 (19% growth in 2018-2019). However, growth in the sales of edible cannabis products hasoutpacedeven these trends: sales of edible expanded 60% from 2019 to 2020 for an estimated market of $1.23 billion.</p><p><blockquote>娱乐性大麻使用的合法化广泛增加了大麻的供应和大麻使用者的数量。在SAMHSA汇编的最新信息（2019年）中，估计上个月美国有3150万12岁以上的人使用大麻。这些比率以每年约10%的速度增长，其中26岁以上成年人的使用量增长最大（2018-2019年增长19%）。然而，食用大麻产品销售的增长超过了这些趋势：从2019年到2020年，食用大麻产品的销售额增长了60%，估计市场为12.3亿美元。</blockquote></p><p> This rise in edible cannabis has had several unintended consequences, in particular a rise in the number of cases of accidental over ingestion. Edibles contain a range of different THC concentrations, including many with several times the average dose for an adult. Also the onset of drug effects for edibles is much longer than for smoked or vaped cannabis products, and this can lead to individuals overconsuming these products under the impression that they have under-dosed.</p><p><blockquote>食用大麻的增加产生了一些意想不到的后果，特别是意外过量摄入病例的增加。食物含有一系列不同浓度的四氢大麻酚，包括许多浓度是成人平均剂量的几倍。此外，食品的药物作用起效时间比吸食或蒸发的大麻产品长得多，这可能导致个人过度消费这些产品，认为他们的剂量不足。</blockquote></p><p> There is evidence that these cases of over-consumption have lead to an increase in the rates of acute cannabinoid intoxication (ACI) requiring medical attention. Poison control centers have documented adramaticincrease in the number of reports involving edible cannabis, rising from 8.4% to 31.2% of reports from 2017 to 2019.</p><p><blockquote>有证据表明，这些过度消费病例导致需要医疗护理的急性大麻素中毒（ACI）发生率增加。毒物控制中心记录了涉及食用大麻的报告数量急剧增加，从2017年到2019年，从8.4%上升到31.2%。</blockquote></p><p> This report also documented the increased risk to children from edibles, with these products making up 48% of reports involving children under 10, despite being only 11.1% of cannabissalesnationwide. The availability of gummies, cookies, brownies, and other sweets likely exacerbates the issue. ACI is a medical emergency in children and isassociatedwith encephalopathy, coma, severe respiratory depression requiringventilation, and evendeath.</p><p><blockquote>该报告还记录了食品对儿童的风险增加，尽管这些产品仅占全国大麻销量的11.1%，但占涉及10岁以下儿童的报告的48%。橡皮糖、饼干、核仁巧克力饼和其他糖果的供应可能会加剧这个问题。ACI是儿童的一种医学急症，与脑病、昏迷、需要通气的严重呼吸抑制甚至死亡有关。</blockquote></p><p> Anebulo Pharmaceuticals developing a treatment to help address the issues of ACI from edibles and other products. The company’s lead compound ANEB-001 is an antagonist of the CB1 receptor responsible for the effects of cannabis and THC intoxication. ANEB-001 works by binding to and blocking these receptors from engaging THC and other cannabinoids (eg. synthetics like K2 or Spice).</p><p><blockquote>Anebulo Pharmaceuticals正在开发一种治疗方法，以帮助解决食品和其他产品引起的ACI问题。该公司的先导化合物ANEB-001是CB1受体的拮抗剂，CB1受体负责大麻和THC中毒的影响。ANEB-001通过结合并阻止这些受体参与THC和其他大麻素（如K2或Spice等合成物质）来发挥作用。</blockquote></p><p> The hope is that this could be used as a quick treatment to alleviate the symptoms and risks of ACI when these patients arrive in the emergency room. There were over 1.7 million estimatedER visitsassociated with cannabis in 2018, or over 1% of all visits to the ER during that year.</p><p><blockquote>希望当这些患者到达急诊室时，这可以作为一种快速治疗方法来缓解ACI的症状和风险。2018年，估计有超过170万次与大麻相关的急诊室就诊，占当年急诊室就诊总数的1%以上。</blockquote></p><p> The drug has already been tested in Phase I clinical studies and shown to be safe across a range of doses. The company is planning on initiation a Phase II clinical study in cannabis smokers in 2021.</p><p><blockquote>该药物已经在I期临床研究中进行了测试，并显示在一系列剂量范围内是安全的。该公司计划于2021年在大麻吸食者中启动II期临床研究。</blockquote></p><p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Cannabis Edibles are Leading to More Negative Outcomes in Cannabis Users<blockquote>大麻食品正在给大麻使用者带来更多负面后果</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nCannabis Edibles are Leading to More Negative Outcomes in Cannabis Users<blockquote>大麻食品正在给大麻使用者带来更多负面后果</blockquote>\n</h2>\n<h4 class=\"meta\">\n<div class=\"head\" \">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/d08bf7808052c0ca9deb4e944cae32aa);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Benzinga </p>\n<p class=\"h-time smaller\">2021-09-20 20:39</p>\n</div>\n</div>\n</h4>\n</header>\n<article>\n<p>The legalization of recreational marijuana use has broadly increased the availability of cannabis and the number of cannabis users. In the latest information (2019) compiled bySAMHSA, an estimated 31.5m individuals over 12 in the US used cannabis in the last month. These rates are growing at approximately 10% per year, with the largest growth in use by adults over 26 (19% growth in 2018-2019). However, growth in the sales of edible cannabis products hasoutpacedeven these trends: sales of edible expanded 60% from 2019 to 2020 for an estimated market of $1.23 billion.</p><p><blockquote>娱乐性大麻使用的合法化广泛增加了大麻的供应和大麻使用者的数量。在SAMHSA汇编的最新信息（2019年）中，估计上个月美国有3150万12岁以上的人使用大麻。这些比率以每年约10%的速度增长，其中26岁以上成年人的使用量增长最大（2018-2019年增长19%）。然而，食用大麻产品销售的增长超过了这些趋势：从2019年到2020年，食用大麻产品的销售额增长了60%，估计市场为12.3亿美元。</blockquote></p><p> This rise in edible cannabis has had several unintended consequences, in particular a rise in the number of cases of accidental over ingestion. Edibles contain a range of different THC concentrations, including many with several times the average dose for an adult. Also the onset of drug effects for edibles is much longer than for smoked or vaped cannabis products, and this can lead to individuals overconsuming these products under the impression that they have under-dosed.</p><p><blockquote>食用大麻的增加产生了一些意想不到的后果，特别是意外过量摄入病例的增加。食物含有一系列不同浓度的四氢大麻酚，包括许多浓度是成人平均剂量的几倍。此外，食品的药物作用起效时间比吸食或蒸发的大麻产品长得多，这可能导致个人过度消费这些产品，认为他们的剂量不足。</blockquote></p><p> There is evidence that these cases of over-consumption have lead to an increase in the rates of acute cannabinoid intoxication (ACI) requiring medical attention. Poison control centers have documented adramaticincrease in the number of reports involving edible cannabis, rising from 8.4% to 31.2% of reports from 2017 to 2019.</p><p><blockquote>有证据表明，这些过度消费病例导致需要医疗护理的急性大麻素中毒（ACI）发生率增加。毒物控制中心记录了涉及食用大麻的报告数量急剧增加，从2017年到2019年，从8.4%上升到31.2%。</blockquote></p><p> This report also documented the increased risk to children from edibles, with these products making up 48% of reports involving children under 10, despite being only 11.1% of cannabissalesnationwide. The availability of gummies, cookies, brownies, and other sweets likely exacerbates the issue. ACI is a medical emergency in children and isassociatedwith encephalopathy, coma, severe respiratory depression requiringventilation, and evendeath.</p><p><blockquote>该报告还记录了食品对儿童的风险增加，尽管这些产品仅占全国大麻销量的11.1%，但占涉及10岁以下儿童的报告的48%。橡皮糖、饼干、核仁巧克力饼和其他糖果的供应可能会加剧这个问题。ACI是儿童的一种医学急症，与脑病、昏迷、需要通气的严重呼吸抑制甚至死亡有关。</blockquote></p><p> Anebulo Pharmaceuticals developing a treatment to help address the issues of ACI from edibles and other products. The company’s lead compound ANEB-001 is an antagonist of the CB1 receptor responsible for the effects of cannabis and THC intoxication. ANEB-001 works by binding to and blocking these receptors from engaging THC and other cannabinoids (eg. synthetics like K2 or Spice).</p><p><blockquote>Anebulo Pharmaceuticals正在开发一种治疗方法，以帮助解决食品和其他产品引起的ACI问题。该公司的先导化合物ANEB-001是CB1受体的拮抗剂，CB1受体负责大麻和THC中毒的影响。ANEB-001通过结合并阻止这些受体参与THC和其他大麻素（如K2或Spice等合成物质）来发挥作用。</blockquote></p><p> The hope is that this could be used as a quick treatment to alleviate the symptoms and risks of ACI when these patients arrive in the emergency room. There were over 1.7 million estimatedER visitsassociated with cannabis in 2018, or over 1% of all visits to the ER during that year.</p><p><blockquote>希望当这些患者到达急诊室时，这可以作为一种快速治疗方法来缓解ACI的症状和风险。2018年，估计有超过170万次与大麻相关的急诊室就诊，占当年急诊室就诊总数的1%以上。</blockquote></p><p> The drug has already been tested in Phase I clinical studies and shown to be safe across a range of doses. The company is planning on initiation a Phase II clinical study in cannabis smokers in 2021.</p><p><blockquote>该药物已经在I期临床研究中进行了测试，并显示在一系列剂量范围内是安全的。该公司计划于2021年在大麻吸食者中启动II期临床研究。</blockquote></p><p></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1194444021","content_text":"The legalization of recreational marijuana use has broadly increased the availability of cannabis and the number of cannabis users. In the latest information (2019) compiled bySAMHSA, an estimated 31.5m individuals over 12 in the US used cannabis in the last month. These rates are growing at approximately 10% per year, with the largest growth in use by adults over 26 (19% growth in 2018-2019). However, growth in the sales of edible cannabis products hasoutpacedeven these trends: sales of edible expanded 60% from 2019 to 2020 for an estimated market of $1.23 billion.\nThis rise in edible cannabis has had several unintended consequences, in particular a rise in the number of cases of accidental over ingestion. Edibles contain a range of different THC concentrations, including many with several times the average dose for an adult. Also the onset of drug effects for edibles is much longer than for smoked or vaped cannabis products, and this can lead to individuals overconsuming these products under the impression that they have under-dosed.\nThere is evidence that these cases of over-consumption have lead to an increase in the rates of acute cannabinoid intoxication (ACI) requiring medical attention. Poison control centers have documented adramaticincrease in the number of reports involving edible cannabis, rising from 8.4% to 31.2% of reports from 2017 to 2019.\nThis report also documented the increased risk to children from edibles, with these products making up 48% of reports involving children under 10, despite being only 11.1% of cannabissalesnationwide. The availability of gummies, cookies, brownies, and other sweets likely exacerbates the issue. ACI is a medical emergency in children and isassociatedwith encephalopathy, coma, severe respiratory depression requiringventilation, and evendeath.\nAnebulo Pharmaceuticals developing a treatment to help address the issues of ACI from edibles and other products. The company’s lead compound ANEB-001 is an antagonist of the CB1 receptor responsible for the effects of cannabis and THC intoxication. ANEB-001 works by binding to and blocking these receptors from engaging THC and other cannabinoids (eg. synthetics like K2 or Spice).\nThe hope is that this could be used as a quick treatment to alleviate the symptoms and risks of ACI when these patients arrive in the emergency room. There were over 1.7 million estimatedER visitsassociated with cannabis in 2018, or over 1% of all visits to the ER during that year.\nThe drug has already been tested in Phase I clinical studies and shown to be safe across a range of doses. The company is planning on initiation a Phase II clinical study in cannabis smokers in 2021.","news_type":1,"symbols_score_info":{}},"isVote":1,"tweetType":1,"viewCount":1084,"commentLimit":10,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"symbols":[],"verified":2,"subType":0,"readableState":1,"langContent":"EN","currentLanguage":"EN","warmUpFlag":false,"orderFlag":false,"shareable":true,"causeOfNotShareable":"","featuresForAnalytics":[],"commentAndTweetFlag":false,"andRepostAutoSelectedFlag":false,"upFlag":false,"length":4,"xxTargetLangEnum":"ORIG"},"commentList":[],"isCommentEnd":true,"isTiger":false,"isWeiXinMini":false,"url":"/m/post/860108150"}