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土豆洋洋
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21:43","market":"us","language":"zh","title":"上涨潜力超100%，这三只股票可“闭眼买”？","url":"https://stock-news.laohu8.com/highlight/detail?id=1195741655","media":"美股研究社","summary":"预计这三只股未来涨幅超100%选举日即将来临，华尔街将赌注押在了民主党的横扫上。在9月29日的总统大选辩论之后，市场上拜登获胜的几率一直在增加。自9月30日以来，标准普尔500指数已上涨5.5%。尽管","content":"<p><img src=\"https://static.tigerbbs.com/6cb7b9ac9d57aaa0d0b1a1a8c64bb785\" tg-width=\"500\" tg-height=\"333\">预计这三只股未来涨幅超100%</p><p>选举日即将来临，华尔街将赌注押在了民主党的横扫上。在9月29日的总统大选辩论之后，市场上拜登获胜的几率一直在增加。</p><p>自9月30日以来，标准普尔500指数已上涨5.5%。尽管如此，投资者转向周期股和小盘股的趋势要明显得多，罗素2000指数同期上涨8.5%。</p><p>分析师Tavis McCour认为，转向周期股和小型股提供了一些证据，显示在民主党大胜的情况下，市场将如何转向，其逻辑是财政支持更强，收益率曲线更陡，周期性复苏更快。\"</p><p>McCour指出，“在此背景下，经济数据具有显著的可持续性，并可能对每股收益产生积极影响。”这位策略师表示，亚特兰大联邦储备银行用于估算实际GDP的GDPNow模型自7月份以来出现了实质性增长，自5月份以来，该公司的分析师几乎每周都倾向于上调对2020年每股收益的预期。他指出，“自8月中旬以来，标准普尔500指数的所有板块对2020年每股盈馀的预期都有所上升(这并不正常)。第三季度的收益应该不错，收益仍然很重要。”</p><p>考虑到这一点，我们将注意力转向了Raymond James支持的三只股票，该公司的分析师指出，每只股票都可能从目前的水平上暴涨超过100%。在TipRanks的数据库中查看这些股票，我们发现华尔街其他分析师也在关注这些股票，它们每个都拥有“强烈购买”的共识评级。</p><p><b>Catalyst Biosciences</b> </p><p>Catalyst Biosciences专注于解决罕见止血和补充介导疾病中未被满足的需求，希望改善世界各地患者的生活。基于开发进度，Raymond James认为其每股4.80美元的股价可能反映出理想的切入点。</p><p>在该公司提供了其主要资产MarzAA和DalcA为第三阶段准备的最新进展后，该公司分析师David Novak指出，他的看涨观点基本没有改变。MarzAA是下一代SQ FVIIa，用于治疗血友病A或B的潜在抑制剂，而DalcA是为血友病B设计的SQ固定剂。</p><p>“我们认为，CBIO的两项三期就绪资产正在抓住重大的市场机会，其股票目前的企业价值在200万美元左右。我们相信，该公司在未来12个月的市场重估中处于有利地位，”Novak评论道。</p><p>Novak强调了它在国际血栓和止血学会(ISTH)虚拟会议上的海报展示，他相信这些数据支持在即将到来的第三阶段的CRIMSON-1试验中为MarzAA选择的剂量方案。最重要的是，在世界血友病联合会虚拟峰会上发布了来自DalcA 2b期试验的强大安全性和有效性数据。</p><p>为此，Novak看到了几个潜在的催化剂。MarzAA的3期试验的首位患者在A2或B血友病患者中的抑制剂定于2020年下半年入组，但这可能会受到冠状病毒病而延迟。此外，MarzAA将在FVII缺乏症患者、血栓性Glanzmann Thrombastenia患者和使用Hemlibra患者中进行1/2期试验，该试验将于2020年底开始。</p><p>Novak认为，修复基因疗法候选方案的宣布和系统性补体抑制剂候选方案都将在2020年晚些时候发布，这将带来更多的利好消息。</p><p>为此，Novak对CBIO的评级为“跑赢大盘”(即买入)，目标价为20美元。如果未来12个月实现这一目标，投资者可能会获得317%的大幅收益。</p><p>其他分析师也的看法也差不多。有3个“买入”评级，没有持有或卖出评级，因此共识评级是一个强劲的“买入”。平均目标价为19.33美元，意味着较当前水平有303%的上涨潜力。</p><p><b>Mirum Pharmaceuticals</b></p><p>Mirum Pharmaceuticals的目标是为肝病患者创造改变生活的疗法，他们相信自己的方法可以解决潜在的原因。在提交一份重要文件之前，Raymond James很喜欢他目前所看到的情况。</p><p>五星级分析师Steven Seedhouse为公司撰文指出,的乐观态度是由MIRM的新计划推动的，该新计划向欧洲药品管理局（EMA）提交了针对maralixibat（MRX）的MAA申请。可能会在2020年第4季度的PFIC2中用于多种适应症。</p><p>尽管此文件将在正在进行的MARCH 3期研究结束之前提交，但Seedhouse指出，此举符合其与EMA的讨论。根据分析师的说法，根据NAPPED进行的统计分析，该数据将第2阶段数据（包括长期无移植存活数据）与自然历史数据进行了比较，EMA已接受MIRM的战略申请全面批准。</p><p>“因此，我们增强了MRX将在PFIC2中获得批准的信心，我们估计将在2022年第一季度实现(高于我们对2H22的估计)，”Seedhouse提到。MRX已经有一个非常大的安全数据库，这有助于他的乐观立场，因为它已经在多个研究中评估了多种适应症(NASH, ALGS和PFIC)。</p><p>此外,第2期INDIGO研究显示，整个PFIC2人群瘙痒改善明显（ItchRO评分），以6名有反应的患者为例，这些患者均患有以非截短性胆盐输出泵（BSEP）蛋白为特征的疾病。大约一半的PFIC患者属于这一类。</p><p>查看MRX五年结果的数据，在7名实现sBA控制的非截断PFIC2患者中建立了无移植生存期。如果那还不够的话，就没有任何临床事件发生，并且7名患者中有2名退出了移植等待名单。</p><p>Seedhouse补充说:“NAPPED协会的自然历史数据进一步支持了这一数据，该数据显示，sBA水平控制在102 mol/ l以下的胆道分流患者15年的原生肝脏生存率为100%。”</p><p>MIRM所具备的一切都说服了Seedhouse对该股给出了强烈的买入评级。他将目标价定为48美元，暗示有140%的上涨潜力。</p><p>其他分析师也同意吗?是的。过去3个月里只发布了买入评级，确切地说是5个买入评级。因此，信息是明确的:MIRM是一个强劲的买入。考虑到49.50美元的平均目标价，该公司股价明年可能飙升150%。</p><p><b>PolyPid </b></p><p>最后但并非最不重要的是PolyPid，其发展局部管理治疗，以改善手术结果。鉴于其PLEX(聚合脂包封基质)技术的强大，这是一个固定在手术部位的平台，可以提供可控和连续的药物输送，Raymond James认为是时候开始行动了。</p><p>该公司今年6月才首次公开募股，就已经给公司分析师Elliot Wilbur留下了深刻印象。看看它的D-PLEX100产品，它在8月份被FDA批准为预防腹部手术后部位感染(SSIs)的快速通道指定。快速通道的设计给了PYPD一个优势，因为它增加了与FDA沟通的频率。此外，它支持滚动提交NDA，允许公司在申请完成时提交部分申请，加快了审查过程。</p><p>“虽然早期的批准不能保证快速通道的指定，但公司和FDA对于D-PLEX100有潜力解决SSI市场未满足的医疗需求的额外资源，应该被视为是积极的”Wilbur说。</p><p>今年7月，PYPD在其随机的SHIELD I试验中招募了第一位患者(手术部位医院获得性感染预防与局部D-plex)，这是评估D-PLEX100在腹部手术后(软组织)手术部位感染的两项三期临床试验中的第一项。主要终点是预防深层或浅层手术部位感染，这是由一个盲性审查委员会在腹部手术后30天内确定的。</p><p>Wilbur期望D-PLEX100在伤口局部应用，并通过数千双膜聚合物和脂质进行延长释放，以提高目前标准护理(SoC)的有效性和安全性，目前的标准护理(SoC)通常需要在切口前注射抗生素。</p><p>应该注意的是,SHIELD I仍有望在全球60个中心招募600-900名患者，从以色列和欧洲的中心开始，然后再继续到美国。“管理层认为该试验的COVID-19大流行预期影响最小，并且可靠的顶线数据（预计于2021年下半年），再加上快速通道名称的好处，可能足以使该药尽早获得批准。”Wilbur说。</p><p>随着SHIELD II计划于2020年末启动，它将作为第二个潜在的确认性第三阶段试验，Wilbur看到了一个激动人心的机会。</p><p>那么，Wilbur站在多头一边也就不足为奇了。除增持评级外，该股目标价仍在23美元，显示出128%的上行潜力。</p><p>华尔街的其他分析师会说什么呢?其他分析师也赞同Wilbur的看法。PYPD的强烈买入共识评级由4个买入评级而来，没有持有或卖出。平均目标价为25.50美元，上涨潜力为153%。</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>上涨潜力超100%，这三只股票可“闭眼买”？</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n上涨潜力超100%，这三只股票可“闭眼买”？\n</h2>\n\n<h4 class=\"meta\">\n\n\n<div class=\"head\" \">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/e09c69c7ea1d4781a9de127f9b375dd6);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">美股研究社 </p>\n<p class=\"h-time\">2020-10-15 21:43</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<p><img src=\"https://static.tigerbbs.com/6cb7b9ac9d57aaa0d0b1a1a8c64bb785\" tg-width=\"500\" tg-height=\"333\">预计这三只股未来涨幅超100%</p><p>选举日即将来临，华尔街将赌注押在了民主党的横扫上。在9月29日的总统大选辩论之后，市场上拜登获胜的几率一直在增加。</p><p>自9月30日以来，标准普尔500指数已上涨5.5%。尽管如此，投资者转向周期股和小盘股的趋势要明显得多，罗素2000指数同期上涨8.5%。</p><p>分析师Tavis McCour认为，转向周期股和小型股提供了一些证据，显示在民主党大胜的情况下，市场将如何转向，其逻辑是财政支持更强，收益率曲线更陡，周期性复苏更快。\"</p><p>McCour指出，“在此背景下，经济数据具有显著的可持续性，并可能对每股收益产生积极影响。”这位策略师表示，亚特兰大联邦储备银行用于估算实际GDP的GDPNow模型自7月份以来出现了实质性增长，自5月份以来，该公司的分析师几乎每周都倾向于上调对2020年每股收益的预期。他指出，“自8月中旬以来，标准普尔500指数的所有板块对2020年每股盈馀的预期都有所上升(这并不正常)。第三季度的收益应该不错，收益仍然很重要。”</p><p>考虑到这一点，我们将注意力转向了Raymond James支持的三只股票，该公司的分析师指出，每只股票都可能从目前的水平上暴涨超过100%。在TipRanks的数据库中查看这些股票，我们发现华尔街其他分析师也在关注这些股票，它们每个都拥有“强烈购买”的共识评级。</p><p><b>Catalyst Biosciences</b> </p><p>Catalyst Biosciences专注于解决罕见止血和补充介导疾病中未被满足的需求，希望改善世界各地患者的生活。基于开发进度，Raymond James认为其每股4.80美元的股价可能反映出理想的切入点。</p><p>在该公司提供了其主要资产MarzAA和DalcA为第三阶段准备的最新进展后，该公司分析师David Novak指出，他的看涨观点基本没有改变。MarzAA是下一代SQ FVIIa，用于治疗血友病A或B的潜在抑制剂，而DalcA是为血友病B设计的SQ固定剂。</p><p>“我们认为，CBIO的两项三期就绪资产正在抓住重大的市场机会，其股票目前的企业价值在200万美元左右。我们相信，该公司在未来12个月的市场重估中处于有利地位，”Novak评论道。</p><p>Novak强调了它在国际血栓和止血学会(ISTH)虚拟会议上的海报展示，他相信这些数据支持在即将到来的第三阶段的CRIMSON-1试验中为MarzAA选择的剂量方案。最重要的是，在世界血友病联合会虚拟峰会上发布了来自DalcA 2b期试验的强大安全性和有效性数据。</p><p>为此，Novak看到了几个潜在的催化剂。MarzAA的3期试验的首位患者在A2或B血友病患者中的抑制剂定于2020年下半年入组，但这可能会受到冠状病毒病而延迟。此外，MarzAA将在FVII缺乏症患者、血栓性Glanzmann Thrombastenia患者和使用Hemlibra患者中进行1/2期试验，该试验将于2020年底开始。</p><p>Novak认为，修复基因疗法候选方案的宣布和系统性补体抑制剂候选方案都将在2020年晚些时候发布，这将带来更多的利好消息。</p><p>为此，Novak对CBIO的评级为“跑赢大盘”(即买入)，目标价为20美元。如果未来12个月实现这一目标，投资者可能会获得317%的大幅收益。</p><p>其他分析师也的看法也差不多。有3个“买入”评级，没有持有或卖出评级，因此共识评级是一个强劲的“买入”。平均目标价为19.33美元，意味着较当前水平有303%的上涨潜力。</p><p><b>Mirum Pharmaceuticals</b></p><p>Mirum Pharmaceuticals的目标是为肝病患者创造改变生活的疗法，他们相信自己的方法可以解决潜在的原因。在提交一份重要文件之前，Raymond James很喜欢他目前所看到的情况。</p><p>五星级分析师Steven Seedhouse为公司撰文指出,的乐观态度是由MIRM的新计划推动的，该新计划向欧洲药品管理局（EMA）提交了针对maralixibat（MRX）的MAA申请。可能会在2020年第4季度的PFIC2中用于多种适应症。</p><p>尽管此文件将在正在进行的MARCH 3期研究结束之前提交，但Seedhouse指出，此举符合其与EMA的讨论。根据分析师的说法，根据NAPPED进行的统计分析，该数据将第2阶段数据（包括长期无移植存活数据）与自然历史数据进行了比较，EMA已接受MIRM的战略申请全面批准。</p><p>“因此，我们增强了MRX将在PFIC2中获得批准的信心，我们估计将在2022年第一季度实现(高于我们对2H22的估计)，”Seedhouse提到。MRX已经有一个非常大的安全数据库，这有助于他的乐观立场，因为它已经在多个研究中评估了多种适应症(NASH, ALGS和PFIC)。</p><p>此外,第2期INDIGO研究显示，整个PFIC2人群瘙痒改善明显（ItchRO评分），以6名有反应的患者为例，这些患者均患有以非截短性胆盐输出泵（BSEP）蛋白为特征的疾病。大约一半的PFIC患者属于这一类。</p><p>查看MRX五年结果的数据，在7名实现sBA控制的非截断PFIC2患者中建立了无移植生存期。如果那还不够的话，就没有任何临床事件发生，并且7名患者中有2名退出了移植等待名单。</p><p>Seedhouse补充说:“NAPPED协会的自然历史数据进一步支持了这一数据，该数据显示，sBA水平控制在102 mol/ l以下的胆道分流患者15年的原生肝脏生存率为100%。”</p><p>MIRM所具备的一切都说服了Seedhouse对该股给出了强烈的买入评级。他将目标价定为48美元，暗示有140%的上涨潜力。</p><p>其他分析师也同意吗?是的。过去3个月里只发布了买入评级，确切地说是5个买入评级。因此，信息是明确的:MIRM是一个强劲的买入。考虑到49.50美元的平均目标价，该公司股价明年可能飙升150%。</p><p><b>PolyPid </b></p><p>最后但并非最不重要的是PolyPid，其发展局部管理治疗，以改善手术结果。鉴于其PLEX(聚合脂包封基质)技术的强大，这是一个固定在手术部位的平台，可以提供可控和连续的药物输送，Raymond James认为是时候开始行动了。</p><p>该公司今年6月才首次公开募股，就已经给公司分析师Elliot Wilbur留下了深刻印象。看看它的D-PLEX100产品，它在8月份被FDA批准为预防腹部手术后部位感染(SSIs)的快速通道指定。快速通道的设计给了PYPD一个优势，因为它增加了与FDA沟通的频率。此外，它支持滚动提交NDA，允许公司在申请完成时提交部分申请，加快了审查过程。</p><p>“虽然早期的批准不能保证快速通道的指定，但公司和FDA对于D-PLEX100有潜力解决SSI市场未满足的医疗需求的额外资源，应该被视为是积极的”Wilbur说。</p><p>今年7月，PYPD在其随机的SHIELD I试验中招募了第一位患者(手术部位医院获得性感染预防与局部D-plex)，这是评估D-PLEX100在腹部手术后(软组织)手术部位感染的两项三期临床试验中的第一项。主要终点是预防深层或浅层手术部位感染，这是由一个盲性审查委员会在腹部手术后30天内确定的。</p><p>Wilbur期望D-PLEX100在伤口局部应用，并通过数千双膜聚合物和脂质进行延长释放，以提高目前标准护理(SoC)的有效性和安全性，目前的标准护理(SoC)通常需要在切口前注射抗生素。</p><p>应该注意的是,SHIELD I仍有望在全球60个中心招募600-900名患者，从以色列和欧洲的中心开始，然后再继续到美国。“管理层认为该试验的COVID-19大流行预期影响最小，并且可靠的顶线数据（预计于2021年下半年），再加上快速通道名称的好处，可能足以使该药尽早获得批准。”Wilbur说。</p><p>随着SHIELD II计划于2020年末启动，它将作为第二个潜在的确认性第三阶段试验，Wilbur看到了一个激动人心的机会。</p><p>那么，Wilbur站在多头一边也就不足为奇了。除增持评级外，该股目标价仍在23美元，显示出128%的上行潜力。</p><p>华尔街的其他分析师会说什么呢?其他分析师也赞同Wilbur的看法。PYPD的强烈买入共识评级由4个买入评级而来，没有持有或卖出。平均目标价为25.50美元，上涨潜力为153%。</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/6cb7b9ac9d57aaa0d0b1a1a8c64bb785","relate_stocks":{"PYPD":"PolyPid Ltd.","CBIO":"Crescent Biopharma Inc","MIRM":"Mirum Pharmaceuticals, Inc."},"is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1195741655","content_text":"预计这三只股未来涨幅超100%选举日即将来临，华尔街将赌注押在了民主党的横扫上。在9月29日的总统大选辩论之后，市场上拜登获胜的几率一直在增加。自9月30日以来，标准普尔500指数已上涨5.5%。尽管如此，投资者转向周期股和小盘股的趋势要明显得多，罗素2000指数同期上涨8.5%。分析师Tavis McCour认为，转向周期股和小型股提供了一些证据，显示在民主党大胜的情况下，市场将如何转向，其逻辑是财政支持更强，收益率曲线更陡，周期性复苏更快。\"McCour指出，“在此背景下，经济数据具有显著的可持续性，并可能对每股收益产生积极影响。”这位策略师表示，亚特兰大联邦储备银行用于估算实际GDP的GDPNow模型自7月份以来出现了实质性增长，自5月份以来，该公司的分析师几乎每周都倾向于上调对2020年每股收益的预期。他指出，“自8月中旬以来，标准普尔500指数的所有板块对2020年每股盈馀的预期都有所上升(这并不正常)。第三季度的收益应该不错，收益仍然很重要。”考虑到这一点，我们将注意力转向了Raymond James支持的三只股票，该公司的分析师指出，每只股票都可能从目前的水平上暴涨超过100%。在TipRanks的数据库中查看这些股票，我们发现华尔街其他分析师也在关注这些股票，它们每个都拥有“强烈购买”的共识评级。Catalyst Biosciences Catalyst Biosciences专注于解决罕见止血和补充介导疾病中未被满足的需求，希望改善世界各地患者的生活。基于开发进度，Raymond James认为其每股4.80美元的股价可能反映出理想的切入点。在该公司提供了其主要资产MarzAA和DalcA为第三阶段准备的最新进展后，该公司分析师David Novak指出，他的看涨观点基本没有改变。MarzAA是下一代SQ FVIIa，用于治疗血友病A或B的潜在抑制剂，而DalcA是为血友病B设计的SQ固定剂。“我们认为，CBIO的两项三期就绪资产正在抓住重大的市场机会，其股票目前的企业价值在200万美元左右。我们相信，该公司在未来12个月的市场重估中处于有利地位，”Novak评论道。Novak强调了它在国际血栓和止血学会(ISTH)虚拟会议上的海报展示，他相信这些数据支持在即将到来的第三阶段的CRIMSON-1试验中为MarzAA选择的剂量方案。最重要的是，在世界血友病联合会虚拟峰会上发布了来自DalcA 2b期试验的强大安全性和有效性数据。为此，Novak看到了几个潜在的催化剂。MarzAA的3期试验的首位患者在A2或B血友病患者中的抑制剂定于2020年下半年入组，但这可能会受到冠状病毒病而延迟。此外，MarzAA将在FVII缺乏症患者、血栓性Glanzmann Thrombastenia患者和使用Hemlibra患者中进行1/2期试验，该试验将于2020年底开始。Novak认为，修复基因疗法候选方案的宣布和系统性补体抑制剂候选方案都将在2020年晚些时候发布，这将带来更多的利好消息。为此，Novak对CBIO的评级为“跑赢大盘”(即买入)，目标价为20美元。如果未来12个月实现这一目标，投资者可能会获得317%的大幅收益。其他分析师也的看法也差不多。有3个“买入”评级，没有持有或卖出评级，因此共识评级是一个强劲的“买入”。平均目标价为19.33美元，意味着较当前水平有303%的上涨潜力。Mirum PharmaceuticalsMirum Pharmaceuticals的目标是为肝病患者创造改变生活的疗法，他们相信自己的方法可以解决潜在的原因。在提交一份重要文件之前，Raymond James很喜欢他目前所看到的情况。五星级分析师Steven Seedhouse为公司撰文指出,的乐观态度是由MIRM的新计划推动的，该新计划向欧洲药品管理局（EMA）提交了针对maralixibat（MRX）的MAA申请。可能会在2020年第4季度的PFIC2中用于多种适应症。尽管此文件将在正在进行的MARCH 3期研究结束之前提交，但Seedhouse指出，此举符合其与EMA的讨论。根据分析师的说法，根据NAPPED进行的统计分析，该数据将第2阶段数据（包括长期无移植存活数据）与自然历史数据进行了比较，EMA已接受MIRM的战略申请全面批准。“因此，我们增强了MRX将在PFIC2中获得批准的信心，我们估计将在2022年第一季度实现(高于我们对2H22的估计)，”Seedhouse提到。MRX已经有一个非常大的安全数据库，这有助于他的乐观立场，因为它已经在多个研究中评估了多种适应症(NASH, ALGS和PFIC)。此外,第2期INDIGO研究显示，整个PFIC2人群瘙痒改善明显（ItchRO评分），以6名有反应的患者为例，这些患者均患有以非截短性胆盐输出泵（BSEP）蛋白为特征的疾病。大约一半的PFIC患者属于这一类。查看MRX五年结果的数据，在7名实现sBA控制的非截断PFIC2患者中建立了无移植生存期。如果那还不够的话，就没有任何临床事件发生，并且7名患者中有2名退出了移植等待名单。Seedhouse补充说:“NAPPED协会的自然历史数据进一步支持了这一数据，该数据显示，sBA水平控制在102 mol/ l以下的胆道分流患者15年的原生肝脏生存率为100%。”MIRM所具备的一切都说服了Seedhouse对该股给出了强烈的买入评级。他将目标价定为48美元，暗示有140%的上涨潜力。其他分析师也同意吗?是的。过去3个月里只发布了买入评级，确切地说是5个买入评级。因此，信息是明确的:MIRM是一个强劲的买入。考虑到49.50美元的平均目标价，该公司股价明年可能飙升150%。PolyPid 最后但并非最不重要的是PolyPid，其发展局部管理治疗，以改善手术结果。鉴于其PLEX(聚合脂包封基质)技术的强大，这是一个固定在手术部位的平台，可以提供可控和连续的药物输送，Raymond James认为是时候开始行动了。该公司今年6月才首次公开募股，就已经给公司分析师Elliot Wilbur留下了深刻印象。看看它的D-PLEX100产品，它在8月份被FDA批准为预防腹部手术后部位感染(SSIs)的快速通道指定。快速通道的设计给了PYPD一个优势，因为它增加了与FDA沟通的频率。此外，它支持滚动提交NDA，允许公司在申请完成时提交部分申请，加快了审查过程。“虽然早期的批准不能保证快速通道的指定，但公司和FDA对于D-PLEX100有潜力解决SSI市场未满足的医疗需求的额外资源，应该被视为是积极的”Wilbur说。今年7月，PYPD在其随机的SHIELD I试验中招募了第一位患者(手术部位医院获得性感染预防与局部D-plex)，这是评估D-PLEX100在腹部手术后(软组织)手术部位感染的两项三期临床试验中的第一项。主要终点是预防深层或浅层手术部位感染，这是由一个盲性审查委员会在腹部手术后30天内确定的。Wilbur期望D-PLEX100在伤口局部应用，并通过数千双膜聚合物和脂质进行延长释放，以提高目前标准护理(SoC)的有效性和安全性，目前的标准护理(SoC)通常需要在切口前注射抗生素。应该注意的是,SHIELD I仍有望在全球60个中心招募600-900名患者，从以色列和欧洲的中心开始，然后再继续到美国。“管理层认为该试验的COVID-19大流行预期影响最小，并且可靠的顶线数据（预计于2021年下半年），再加上快速通道名称的好处，可能足以使该药尽早获得批准。”Wilbur说。随着SHIELD 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