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2022-01-13

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Salarius Plans To Enter $15B Protein Degradation Space With DeuteRx Deal<blockquote>Salarius 计划通过 DeuteRx 交易进入价值 150 亿美元的蛋白质降解领域</blockquote>

Salarius Pharmaceuticals Inc has agreed to acquire an oral, small molecule targeted protein degradat

Salarius Plans To Enter $15B Protein Degradation Space With DeuteRx Deal<blockquote>Salarius 计划通过 DeuteRx 交易进入价值 150 亿美元的蛋白质降解领域</blockquote>

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Molecular glues are small molecules that commandeer the body&#39;s normal protein-degradation processes and induce selective elimination of cancer-causing proteins.</li><li>Salarius plans to begin the first clinical trial in 2023.</li><li>As part of the agreement, Salarius and DeuteRx will collaborate to complete SP-3164 development activities and collaborate on the R&amp;D of future products.</li><li>Under the agreement terms, DeuteRx will receive an upfront payment consisting of $1.5 million in cash and 1 million shares of restricted stock.</li><li>SP-3164, DeuteRx is also entitled to receive up to $188 in milestone payments.</li><li>Additionally, DeuteRx is eligible to receive milestone payments of up to $84 million for each of two future products.</li><li><b>Price Action:</b> SLRX shares traded 1.52% higher at $0.50 premarket on the last check Thursday.</li></ul></body></html></p><p><blockquote><ul><li>此次收购包括 Salarius 已将其更名为 SP-3164（以前称为 DRX-164）的主要候选药物。</li><li>Salarius 首席执行官 David Arthur 表示：“此次战略收购对于 Salarius 来说是一个变革性事件，它显着扩展了我们的开发管道，同时建立了我们领先的临床阶段候选药物 seclidemstat 的势头。”</li><li>SP-3164是下一代cereblon结合分子胶。分子胶是小分子，可以征用人体正常的蛋白质降解过程，并诱导致癌蛋白质的选择性消除。</li><li>Salarius 计划于 2023 年开始首次临床试验。</li><li>作为协议的一部分，Salarius和DeuteRx将合作完成SP-3164开发活动，并在未来产品的研发上进行合作。</li><li>根据协议条款，DeuteRx 将收到预付款，包括 150 万美元现金和 100 万股限制性股票。</li><li>SP-3164，DeuteRx还有权获得高达188美元的里程碑付款。</li><li>此外，DeuteRx 有资格为两款未来产品分别获得高达 8400 万美元的里程碑付款。</li><li><b>价格行为：</b>周四最后一次检查时，SLRX 股价盘前上涨 1.52%，至 0.50 美元。</li></ul></blockquote></p><p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; 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color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nSalarius Plans To Enter $15B Protein Degradation Space With DeuteRx Deal<blockquote>Salarius 计划通过 DeuteRx 交易进入价值 150 亿美元的蛋白质降解领域</blockquote>\n</h2>\n<h4 class=\"meta\">\n<div class=\"head\" \">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/d08bf7808052c0ca9deb4e944cae32aa);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Benzinga Earnings </p>\n<p class=\"h-time smaller\">2022-01-13 22:04</p>\n</div>\n</div>\n</h4>\n</header>\n<article>\n<p><html><head></head><body><b>Salarius Pharmaceuticals Inc</b> has agreed to acquire an oral, small molecule targeted protein degradation portfolio against cancer from <b>DeuteRx LLC</b>.</p><p><blockquote><html><head></head><body><b>萨拉里乌斯制药公司</b>已同意从<b>杜特克斯有限责任公司</b>.</body></html></blockquote></p><p><ul><li>The acquisition includes a lead drug candidate that Salarius has renamed SP-3164 (formerly DRX-164).</li><li>&#34;This strategic acquisition is a transformative event for Salarius that significantly expands our development pipeline while building upon the momentum of our lead clinical-stage candidate, seclidemstat,&#34; stated David Arthur, CEO of Salarius.</li><li>SP-3164 is a next-generation cereblon-binding molecular glue. Molecular glues are small molecules that commandeer the body&#39;s normal protein-degradation processes and induce selective elimination of cancer-causing proteins.</li><li>Salarius plans to begin the first clinical trial in 2023.</li><li>As part of the agreement, Salarius and DeuteRx will collaborate to complete SP-3164 development activities and collaborate on the R&amp;D of future products.</li><li>Under the agreement terms, DeuteRx will receive an upfront payment consisting of $1.5 million in cash and 1 million shares of restricted stock.</li><li>SP-3164, DeuteRx is also entitled to receive up to $188 in milestone payments.</li><li>Additionally, DeuteRx is eligible to receive milestone payments of up to $84 million for each of two future products.</li><li><b>Price Action:</b> SLRX shares traded 1.52% higher at $0.50 premarket on the last check Thursday.</li></ul></body></html></p><p><blockquote><ul><li>此次收购包括 Salarius 已将其更名为 SP-3164（以前称为 DRX-164）的主要候选药物。</li><li>Salarius 首席执行官 David Arthur 表示：“此次战略收购对于 Salarius 来说是一个变革性事件，它显着扩展了我们的开发管道，同时建立了我们领先的临床阶段候选药物 seclidemstat 的势头。”</li><li>SP-3164是下一代cereblon结合分子胶。分子胶是小分子，可以征用人体正常的蛋白质降解过程，并诱导致癌蛋白质的选择性消除。</li><li>Salarius 计划于 2023 年开始首次临床试验。</li><li>作为协议的一部分，Salarius和DeuteRx将合作完成SP-3164开发活动，并在未来产品的研发上进行合作。</li><li>根据协议条款，DeuteRx 将收到预付款，包括 150 万美元现金和 100 万股限制性股票。</li><li>SP-3164，DeuteRx还有权获得高达188美元的里程碑付款。</li><li>此外，DeuteRx 有资格为两款未来产品分别获得高达 8400 万美元的里程碑付款。</li><li><b>价格行为：</b>周四最后一次检查时，SLRX 股价盘前上涨 1.52%，至 0.50 美元。</li></ul></blockquote></p><p></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{},"source_url":"","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1128321741","content_text":"Salarius Pharmaceuticals Inc has agreed to acquire an oral, small molecule targeted protein degradation portfolio against cancer from DeuteRx LLC.The acquisition includes a lead drug candidate that Salarius has renamed SP-3164 (formerly DRX-164).\"This strategic acquisition is a transformative event for Salarius that significantly expands our development pipeline while building upon the momentum of our lead clinical-stage candidate, seclidemstat,\" stated David Arthur, CEO of Salarius.SP-3164 is a next-generation cereblon-binding molecular glue. 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Salarius Plans To Enter $15B Protein Degradation Space With DeuteRx Deal<blockquote>Salarius 计划通过 DeuteRx 交易进入价值 150 亿美元的蛋白质降解领域</blockquote>

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