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2021-10-19

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Entasis Therapeutics soared over 26% in premarket trading<blockquote>Entasis Therapeutics在盘前交易中飙升超过26%</blockquote>

Entasis Therapeutics Holdings Inc. says primary endpoint met in late-stage trial for SUL-DUR in Acin

Entasis Therapeutics soared over 26% in premarket trading<blockquote>Entasis Therapeutics在盘前交易中飙升超过26%</blockquote>

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Take a look at Seeking&nbsp;Alpha's Stocks on the Move.<blockquote>对当今市场上最大的赢家和输家的实时更新感兴趣吗？看看Seeking Alpha的股票走势。</blockquote>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Entasis Therapeutics soared over 26% in premarket trading<blockquote>Entasis Therapeutics在盘前交易中飙升超过26%</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nEntasis Therapeutics soared over 26% in premarket trading<blockquote>Entasis Therapeutics在盘前交易中飙升超过26%</blockquote>\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\nTiger Newspress \n2021-10-19 16:08\n</div>\n</a>\n</h4>\n</header>\n<article>\n<a href=\"https://laohu8.com/S/ETTX\">Entasis Therapeutics Holdings Inc.</a> says primary endpoint met in late-stage trial for SUL-DUR in Acinetobacter infections.<blockquote><a href=\"https://laohu8.com/S/ETTX\">恩塔西斯治疗控股公司。</a>表示SUL-DUR治疗不动杆菌感染的后期试验达到了主要终点。</blockquote> <img src=\"https://static.tigerbbs.com/6dfdb354decf318b731b62985eaf45b8\" tg-width=\"981\" tg-height=\"559\" referrerpolicy=\"no-referrer\"><blockquote></blockquote> Announcing topline results from a Phase 3 registrational trial for SUL-DUR, Entasis Therapeutics(NASDAQ:ETTX)says that the 207-patient study met the primary endpoint for patients withcarbapenem-resistantAcinetobacterinfections.<blockquote>Entasis Therapeutics（纳斯达克股票代码：ETTX）宣布了SUL-DUR 3期注册试验的主要结果，表示这项涉及207名患者的研究达到了碳青霉烯类耐药患者的主要终点不动杆菌感染。</blockquote> Entasis (ETTX) have&nbsp;added ~26.7%in the pre-market.<blockquote>Entasis(ETTX)在盘前上涨了约26.7%。</blockquote> On the tolerability front, the two-part study reached the primary safety objective showing a decline in nephrotoxicity with statistical significance.<blockquote>在耐受性方面，两部分研究达到了主要安全性目标，显示肾毒性下降具有统计学意义。</blockquote> In the CRABC m-MITT population (n=125) of Part A of the study, 28-day all-cause mortality stood at 19.0% (12/63) compared to 32.3% (20/62) in the colistin arm, indicating the achievement of the primary endpoint with statistical non-inferiority versus colistin.<blockquote>在研究A部分的CRABC m-MITT人群（n=125）中，28天全因死亡率为19.0%（12/63），而粘菌素组为32.3%（20/62），表明达到了主要终点，与粘菌素相比具有统计学上的非劣效性。</blockquote> The clinical cure at Test of Cure (TOC) reached 61.9% in the SUL-DUR arm compared to 40.3% in the colistin arm showing statistical significance.<blockquote>SUL-DUR组的临床治愈率（TOC）达到61.9%，而粘菌素组为40.3%，显示出统计学意义。</blockquote> ~88% of patients who received SUL-DUR experienced adverse events (AEs) versus ~94% and ~89% in the colistin arms Part A and B, respectively, showing a comparable safety profile for the experimental therapy.<blockquote>接受SUL-DUR治疗的患者中约有88%发生了不良事件（AE），而粘菌素组A部分和B部分分别为约94%和约89%，显示出实验性治疗的安全性相当。</blockquote> “We look forward to discussing our data with the regulatory agencies and preparing our first regulatory submission in mid-2022,” CEO Manos Perros remarked.<blockquote>首席执行官Manos Perros表示：“我们期待与监管机构讨论我们的数据，并在2022年中期准备第一份监管文件。”</blockquote> Interested in real-time updates on the biggest gainers and losers in the market today? Take a look at Seeking&nbsp;Alpha's Stocks on the Move.<blockquote>对当今市场上最大的赢家和输家的实时更新感兴趣吗？看看Seeking Alpha的股票走势。</blockquote>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"ETTX":"Entasis Therapeutics Holdings Inc."},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1186895664","content_text":"Entasis Therapeutics Holdings Inc. says primary endpoint met in late-stage trial for SUL-DUR in Acinetobacter infections.\n\nAnnouncing topline results from a Phase 3 registrational trial for SUL-DUR, Entasis Therapeutics(NASDAQ:ETTX)says that the 207-patient study met the primary endpoint for patients withcarbapenem-resistantAcinetobacterinfections.\nEntasis (ETTX) have added ~26.7%in the pre-market.\nOn the tolerability front, the two-part study reached the primary safety objective showing a decline in nephrotoxicity with statistical significance.\nIn the CRABC m-MITT population (n=125) of Part A of the study, 28-day all-cause mortality stood at 19.0% (12/63) compared to 32.3% (20/62) in the colistin arm, indicating the achievement of the primary endpoint with statistical non-inferiority versus colistin.\nThe clinical cure at Test of Cure (TOC) reached 61.9% in the SUL-DUR arm compared to 40.3% in the colistin arm showing statistical significance.\n~88% of patients who received SUL-DUR experienced adverse events (AEs) versus ~94% and ~89% in the colistin arms Part A and B, respectively, showing a comparable safety profile for the experimental therapy.\n“We look forward to discussing our data with the regulatory agencies and preparing our first regulatory submission in mid-2022,” CEO Manos Perros remarked.\nInterested in real-time updates on the biggest gainers and losers in the market today? Take a look at Seeking Alpha's Stocks on the Move.","news_type":1,"symbols_score_info":{"ETTX":0.9}},"isVote":1,"tweetType":1,"viewCount":3733,"commentLimit":10,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"symbols":[],"verified":2,"subType":0,"readableState":1,"langContent":"CN","currentLanguage":"CN","warmUpFlag":false,"orderFlag":false,"shareable":true,"causeOfNotShareable":"","featuresForAnalytics":[],"commentAndTweetFlag":false,"andRepostAutoSelectedFlag":false,"upFlag":false,"length":5,"xxTargetLangEnum":"ZH_CN"},"commentList":[],"hasMoreComment":false,"orderType":2}

Entasis Therapeutics soared over 26% in premarket trading<blockquote>Entasis Therapeutics在盘前交易中飙升超过26%</blockquote>

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