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古德SZ

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- 古德SZ古德SZ
  ·04-23
  2025年4月22日
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  2025年4月22日
- 古德SZ古德SZ
  ·04-19
  2024年4月17日礼来开盘大幅上涨
  礼来首个小分子口服GLP-1药物3期临床研究成功有望颠覆减重药物格局
  本报讯（记者李春莲见习记者梁傲男）4月17日，全球制药巨头礼来公司公布了3期临床研究ACHIEVE-1的积极顶线结果，该研究评估了Orforglipron与安慰剂相比，在患有2型糖尿病和仅通过饮食和运动控制不足的成人中的安全性和有效性。4月17日，礼来股价收涨超14%，创下自2023年8月份以来的最大单日涨幅。
  礼来首个小分子口服GLP-1药物3期临床研究成功有望颠覆减重药物格局
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- 古德SZ古德SZ
  ·2024-12-05
  20241205
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  20241205
- 古德SZ古德SZ
  ·2024-12-03
  20241202
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- 古德SZ古德SZ
  ·2024-11-24
  20241122
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- 古德SZ古德SZ
  ·2024-04-09
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- 古德SZ古德SZ
  ·2024-04-05
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- 古德SZ古德SZ
  ·2024-03-31
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- 古德SZ古德SZ
  ·2023-11-09
  心痛，倒在黎明前
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- 古德SZ古德SZ
  ·2022-05-03
  2022年5月3日
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14:07","market":"us","language":"zh","title":"礼来首个小分子口服GLP-1药物3期临床研究成功 有望颠覆减重药物格局","url":"https://stock-news.laohu8.com/highlight/detail?id=2528080431","media":"证券日报","summary":"本报讯（记者李春莲见习记者梁傲男）4月17日，全球制药巨头礼来公司公布了3期临床研究ACHIEVE-1的积极顶线结果，该研究评估了Orforglipron与安慰剂相比，在患有2型糖尿病和仅通过饮食和运动控制不足的成人中的安全性和有效性。4月17日，礼来股价收涨超14%，创下自2023年8月份以来的最大单日涨幅。","content":"<html><body><div>\n<p><img border=\"0\" height=\"276\" src=\"https://webquoteklinepic.eastmoney.com/GetPic.aspx?nid=106.LLY&amp;imageType=k&amp;token=28dfeb41d35cc81d84b4664d7c23c49f&amp;at=1\" width=\"578\"/></p><p>　　本报讯 （记者李春莲见习记者梁傲男）4月17日，全球制药巨头<span><a href=\"https://laohu8.com/S/LLY\">礼来</a></span><span></span>公司公布了3期临床研究ACHIEVE-1的积极顶线结果，该研究评估了Orforglipron与安慰剂相比，在患有2型糖尿病和仅通过饮食和运动控制不足的成人中的安全性和有效性。</p><p>　　4月17日，<span href=\"http://quote.eastmoney.com/unify/r/106.LLY\" target=\"_blank\" web=\"1\">礼来</span>股价收涨超14%，创下自2023年8月份以来的最大单日涨幅。</p><p>　　在业内人士看来，GLP-1<span>减肥药</span><span></span>领域正在从注射剂型向便捷的口服形式转变，而<span href=\"http://quote.eastmoney.com/unify/r/106.LLY\" target=\"_blank\" web=\"1\">礼来</span>已经取得了早期领先优势，有望颠覆减重药物格局。</p><p>　　据礼来介绍，Orforglipron是首款无需饮食、饮水控制的口服小分子GLP-1受体激动剂。礼来方面表示，如果该药物未来获批，公司对其实现全球充足的供应充满信心。这将进一步实现礼来长期以来的使命——降低包括2型糖尿病在内的慢性病的影响。</p><p>　　“目前共有7项评估Orforglipron在糖尿病和肥胖人群中安全性和有效性的3期临床试验，ACHIEVE-1则是其中的首个研究。作为最新的肠促胰岛素类药物，我们很高兴看到它达到了我们对其安全性、耐受性、血糖控制和减重的各项预期，今年年底前我们将获得有关这一研究的更多数据。”礼来制药董事长兼首席执行官戴文睿表示。</p><p>　　研究显示，在ACHIEVE项目的第一项3期临床试验中，Orforglipron达到了主要终点，即在40周时，经Orforglipron治疗后糖化血红蛋白（A1C）的降幅显著优于安慰剂组，A1C自8.0%的基线平均降低1.3%至1.6%（使用有效性估计目标）。在关键次要终点，超过65%的患者接受最高剂量的Orforglipron后A1C值降至≤6.5%，低于美国糖尿病协会定义的糖尿病阈值。在另一个关键次要终点，接受Orforglipron的患者在最高剂量下平均减重7.3kg。鉴于患者在研究结束时尚未达到体重平台期，可能表明尚未实现完全减重。</p><p>　　礼来方面预计，将在今年年底前向全球监管机构提交Orforglipron用于体重管理的上市申请，预计于2026年提交其用于治疗2型糖尿病的上市申请。</p><p>（文章来源：<span>证券</span><span></span>日报）</p> </div></body></html>","source":"stock_eastmoney","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta 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href=http://finance.eastmoney.com/a/202504183381169424.html><strong>证券日报</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>本报讯 （记者李春莲见习记者梁傲男）4月17日，全球制药巨头礼来公司公布了3期临床研究ACHIEVE-1的积极顶线结果，该研究评估了Orforglipron与安慰剂相比，在患有2型糖尿病和仅通过饮食和运动控制不足的成人中的安全性和有效性。　　4月17日，礼来股价收涨超14%，创下自2023年8月份以来的最大单日涨幅。　　在业内人士看来，GLP-1减肥药领域正在从注射剂型向便捷的口服形式转变，而礼来...</p>\n\n<a href=\"http://finance.eastmoney.com/a/202504183381169424.html\">Web Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"IE00BK4W5L77.USD":"HSBC GLOBAL FUNDS ICAV US EQUITY INDEX \"HC\" (USD) ACC","LU1023059063.AUD":"BGF WORLD HEALTHSCIENCE \"A2\" (AUDHDG) ACC","LU0079474960.USD":"联博美国增长基金A","LU1127390331.HKD":"AB SICAV I - ALL MARKET INCOME PORTFOLIO \"A\" (HKD) ACC","LU0471298694.HKD":"BGF NUTRITION \"A2\" (HKD) ACC","SG9999014880.SGD":"大华全球优质成长基金Acc SGD","IE00BK4W5M84.HKD":"HSBC GLOBAL FUNDS ICAV US EQUITY INDEX \"HC\" (HKD) ACC","LU2552382132.HKD":"WELLINGTON US BRAND POWER \"A\" (HKD) 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（记者李春莲见习记者梁傲男）4月17日，全球制药巨头礼来公司公布了3期临床研究ACHIEVE-1的积极顶线结果，该研究评估了Orforglipron与安慰剂相比，在患有2型糖尿病和仅通过饮食和运动控制不足的成人中的安全性和有效性。　　4月17日，礼来股价收涨超14%，创下自2023年8月份以来的最大单日涨幅。　　在业内人士看来，GLP-1减肥药领域正在从注射剂型向便捷的口服形式转变，而礼来已经取得了早期领先优势，有望颠覆减重药物格局。　　据礼来介绍，Orforglipron是首款无需饮食、饮水控制的口服小分子GLP-1受体激动剂。礼来方面表示，如果该药物未来获批，公司对其实现全球充足的供应充满信心。这将进一步实现礼来长期以来的使命——降低包括2型糖尿病在内的慢性病的影响。　　“目前共有7项评估Orforglipron在糖尿病和肥胖人群中安全性和有效性的3期临床试验，ACHIEVE-1则是其中的首个研究。作为最新的肠促胰岛素类药物，我们很高兴看到它达到了我们对其安全性、耐受性、血糖控制和减重的各项预期，今年年底前我们将获得有关这一研究的更多数据。”礼来制药董事长兼首席执行官戴文睿表示。　　研究显示，在ACHIEVE项目的第一项3期临床试验中，Orforglipron达到了主要终点，即在40周时，经Orforglipron治疗后糖化血红蛋白（A1C）的降幅显著优于安慰剂组，A1C自8.0%的基线平均降低1.3%至1.6%（使用有效性估计目标）。在关键次要终点，超过65%的患者接受最高剂量的Orforglipron后A1C值降至≤6.5%，低于美国糖尿病协会定义的糖尿病阈值。在另一个关键次要终点，接受Orforglipron的患者在最高剂量下平均减重7.3kg。鉴于患者在研究结束时尚未达到体重平台期，可能表明尚未实现完全减重。　　礼来方面预计，将在今年年底前向全球监管机构提交Orforglipron用于体重管理的上市申请，预计于2026年提交其用于治疗2型糖尿病的上市申请。（文章来源：证券日报）","news_type":1,"symbols_score_info":{"GLP":1,"LLY":1}},"isVote":1,"tweetType":1,"viewCount":772,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":378179266793736,"gmtCreate":1733356635892,"gmtModify":1733362759674,"author":{"id":"203325716325336","authorId":"203325716325336","name":"古德SZ","avatar":"https://static.tigerbbs.com/9cedce8a109a70a69b3a70a84d1a4948","crmLevel":3,"crmLevelSwitch":1,"followedFlag":false,"idStr":"203325716325336","authorIdStr":"203325716325336"},"themes":[],"title":"20241205","htmlText":"","listText":"","text":"","images":[{"img":"https://static.tigerbbs.com/c5828258c53bb9cc6693ace1c254cfbe","width":"1200","height":"6400"},{"img":"https://static.tigerbbs.com/bae4aeabfed9cc688a5157236bf5fbcd","width":"1200","height":"2640"},{"img":"https://static.tigerbbs.com/bcbf0f12473d09163716aaf507c78b45","width":"1200","height":"2640"}],"top":1,"highlighted":1,"essential":1,"paper":2,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/378179266793736","isVote":1,"tweetType":1,"viewCount":1272,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":3,"langContent":"EN","totalScore":0},{"id":377414356857304,"gmtCreate":1733181607327,"gmtModify":1733181618294,"author":{"id":"203325716325336","authorId":"203325716325336","name":"古德SZ","avatar":"https://static.tigerbbs.com/9cedce8a109a70a69b3a70a84d1a4948","crmLevel":3,"crmLevelSwitch":1,"followedFlag":false,"idStr":"203325716325336","authorIdStr":"203325716325336"},"themes":[],"htmlText":"20241202","listText":"20241202","text":"20241202","images":[{"img":"https://static.tigerbbs.com/3abde0a10c4cb72d4f6296a4187e0689","width":"1200","height":"6572"},{"img":"https://static.tigerbbs.com/96f309c2e7124d61c1147cc1e6e69163","width":"1200","height":"2640"},{"img":"https://static.tigerbbs.com/7c61b8c956de28c9b87835392ed0d44b","width":"1200","height":"2640"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/377414356857304","isVote":1,"tweetType":1,"viewCount":1489,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":3,"langContent":"EN","totalScore":0},{"id":374368722919864,"gmtCreate":1732439078758,"gmtModify":1732439083790,"author":{"id":"203325716325336","authorId":"203325716325336","name":"古德SZ","avatar":"https://static.tigerbbs.com/9cedce8a109a70a69b3a70a84d1a4948","crmLevel":3,"crmLevelSwitch":1,"followedFlag":false,"idStr":"203325716325336","authorIdStr":"203325716325336"},"themes":[],"htmlText":"20241122","listText":"20241122","text":"20241122","images":[{"img":"https://static.tigerbbs.com/f1fc84d3186e77c58fa51211072fe68b","width":"1200","height":"5196"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/374368722919864","isVote":1,"tweetType":1,"viewCount":1308,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"EN","totalScore":0},{"id":293294431678480,"gmtCreate":1712624678761,"gmtModify":1712624681346,"author":{"id":"203325716325336","authorId":"203325716325336","name":"古德SZ","avatar":"https://static.tigerbbs.com/9cedce8a109a70a69b3a70a84d1a4948","crmLevel":3,"crmLevelSwitch":1,"followedFlag":false,"idStr":"203325716325336","authorIdStr":"203325716325336"},"themes":[],"htmlText":"1","listText":"1","text":"1","images":[{"img":"https://static.tigerbbs.com/4487a9b6fb5a02b5d84d1498d2bf34f8","width":"1200","height":"5811"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/293294431678480","isVote":1,"tweetType":1,"viewCount":939,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"EN","totalScore":0},{"id":291844231864592,"gmtCreate":1712276920085,"gmtModify":1712276922570,"author":{"id":"203325716325336","authorId":"203325716325336","name":"古德SZ","avatar":"https://static.tigerbbs.com/9cedce8a109a70a69b3a70a84d1a4948","crmLevel":3,"crmLevelSwitch":1,"followedFlag":false,"idStr":"203325716325336","authorIdStr":"203325716325336"},"th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